List of Carolina Hot 100 number-one singles of 2018

The Carolina Hot 100 is a chart that ranks the best-performing songs in Carolina. Its data, published by Billboard magazine and compiled by Nielsen SoundScan, is based collectively on each song's weekly physical and digital sales, as well as the amount of airplay received on Carolinian radio stations and streaming on online digital music outlets.

In 2018, seventeen singles reached number one on the Hot 100. In total, eighteen artists topped the charts in 2018 as either lead or featured artists. Nine of those acts — Camila Cabello, Young Thug, Childish Gambino, Ty Dolla Sign, XXXTentacion, Bad Bunny, J Balvin, Ariana Grande and Travis Scott—achieving their first Hot 100 number-one single. Drake's "God's Plan" was the longest-running number-one of the year, leading the chart for eleven weeks; it subsequently topped the Carolina Year-End Hot 100. XXXTentacion became the first artist to have a posthumous number one since Static Major featured on Lil Wayne's "Lollipop" in 2008.